Author’s response to “Optimal paricalcitol starting dose for parathyroid hormone suppression in secondary hyperparathyroidism”

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Author's response to reviews Title:Relationship between parathyroid mass and parathyroid hormone level in hemodialysis patients with secondary hyperparathyroidism Authors:

23 Background: To evaluate the influence of parathyroid mass on the regulation of 24 parathyroid hormone (PTH) secretion, we investigated the relationship between the 25 resected parathyroid gland in total parathyroidectomy and the parathyroid hormone 26 level in hemodialysis patients with secondary hyperparathyroidism. 27 Methods: From January 2009 to July 2014, 223 patients undergoing total 2...

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Paricalcitol for secondary hyperparathyroidism in renal transplantation.

Secondary hyperparathyroidism contributes to post-transplant CKD mineral and bone disorder. Paricalcitol, a selective vitamin D receptor activator, decreased serum parathyroid hormone levels and proteinuria in patients with secondary hyperparathyroidism. This single-center, prospective, randomized, crossover, open-label study compared the effect of 6-month treatment with paricalcitol (1 μg/d fo...

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Parathyroid hormone between limits and possibilities in secondary hyperparathyroidism

Introduction Renal hyperparathyroidism is a major clinical problem resulting in elevated serum parathyroid hormone (PTH) levels. This condition is often called secondary hyperparathyroidism (SHPT), although the parathyroid cells changed their secretion of PTH from a secondary (reactive) pattern to a primary (autonomous) pattern. In the following sections, secondary hyperparathyroidism is used s...

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Dynamics of parathyroid hormone secretion in health and secondary hyperparathyroidism.

This review examines the dynamics of parathyroid hormone secretion in health and in various causes of secondary hyperparathyroidism. Although most studies of parathyroid hormone and calcium have focused on the modification of parathyroid hormone secretion by serum calcium, the relationship between parathyroid hormone and serum calcium is bifunctional because parathyroid hormone also modifies se...

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Relationship between Basal Metabolic Rate and Serum Parathyroid Hormone and Body Composition in Women with Secondary Hyperparathyroidism

Introduction: Several factors including fat free mass and fat mass can affect Basal Metabolic Rate (BMR) as the largest component of daily energy demand. The aim of the current cross-sectional study was to compare BMR in women with secondary hyperparathyroidism and healthy women and to evaluate its relationship with serum Parathyroid Hormone (PTH), fat free mass and fat mass in these subjects. ...

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ژورنال

عنوان ژورنال: Nature Clinical Practice Nephrology

سال: 2007

ISSN: 1745-8323,1745-8331

DOI: 10.1038/ncpneph0449